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Here's what makes this topic more complex than a simple yes-or-no answer: 5-Amino-1MQ functions as a non-competitive inhibitor of nicotinamide N-methyltransferase (NNMT), the enzyme that methylates nicotinamide into N-methyl nicotinamide
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Its primary mechanism is believed to pivot around enhancing lipolysis, the breakdown of fat, and suppressing lipogenesis, the process of fat accumulation [More et al., 2014]
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