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Glutathione-responsive self-delivery nanoparticles assembled by curcumin dimer for enhanced intracellular drug delivery - ScienceDirect
It serves as an obligate co-substrate for multiple enzyme families, including glutathione peroxidases (GPx), glutathione S-transferases (GST), and glutaredoxins, where it contributes to redox-regulated biochemical pathways and enzyme-mediated signaling processes
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This study pioneers the use of the pulmonary surfactant recycling mechanism for cooperative drug delivery, offering a novel targeted platform for IPF
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