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The authors reported that there was no clear correlation between the endoscopic appearances and the histologic findings, although none of the findings from the 12 subjects were seen in a series of five ileocolonic biopsies from age-matched and site-matched controls with normal mucosa
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Key finding: Dose-dependent collagen synthesis and glycosaminoglycan production in fibroblasts, with significant increases in extracellular matrix deposition
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