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Upon modification, RTL1 RNA-cleaving activity is inhibited
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Capsules:60 capsules
One patient with the combination of del(17p) and chromosome 12 trisomy had an abnormally high level of mitochondrial superoxide after AZD-5991 and ibrutinib treatment (a 551-fold increase while on ibrutinib alone and a 74-fold increase while on combination treatment with ibrutinib and CB-839
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