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Autoimmune Diseases Result from a Breakdown of Self-Tolerance Leading to the Generation of Immune Response to Self-Antigens Autoimmune diseases are manifestations of a series of events that involve an interplay between genetic and environmental factors, leading to a breakdown of self-tolerance and activation of potentially self-reactive T cells [4,5,47,48,49]
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[DOI] [PubMed] [Google Scholar] 119.Tang LQ, et al
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