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Ethanol-Induced Gastric Ulcer In acute ethanol-induced gastric ulcer model, carbenoxolone (100 mg/kg) and (-)-Carveol (25, 50, 100 and 200 mg/kg, p.o.) significantly reduced ULA to 87% (30.0 ± 6.0 mm 2 ), 46% (126.9 ± 15.3 mm 2 ), 70% (69.9 ± 9.5 mm 2 ), 91% (20.2 ± 4.7 mm 2 ) and 93% (16.4 ± 4.5 mm 2 ) respectively, when compared to the control group (235.7 ± 9.9 mm 2 ) (Figures 1, 2)
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Several major ingredients of FRP were separated and identified by using methods reported in the literature (Zhang et al., 2008