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In CHD, acute coronary syndrome (ACS), and ischemic cardiomyopathy, HDL have reduced ability to inhibit oxidation of LDL, likely through reduced PON1 levels as reported in CHD (845,863,864)

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The HOAc (acetate) salt form offers clean aqueous dissolution with no co-solvents required, simplifying incorporation into pH 5.0–7.0 serums, tonics and scalp leave-on systems